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Scientist (LC/MS)

BioAgilytix Labs, 2300 Englert Drive, Durham, North Carolina, Vereinigte Staaten von Amerika Erf #187
Dienstag, 5. Juli 2022

In this role, you will lead the design, development, and execution of bioanalytical experiments to bring new therapies to market. This role is very exciting due to our wide variety of clients and broad ranges of medicine treating different types of diseases. You’ll work in a milestone driven environment generating data, evaluating the performance of the medicine and context of use. Data integrity and quality are important to us, and this role will integrate the expectations in a highly regulated setting.


We are looking for candidates who get energized by working with the newest bioanalytical technologies to solve complex challenges. The best candidates are curious and continuous learners, who have experience in a highly regulated environment, where data integrity is expected and honored. You’ll enjoy and crave collaboration with a network of expert scientists, all while welcoming the opportunity to manage multiple projects, sponsors and project timelines. If you are adaptable and able to inspire the best results, then you’ll be right at home here at BioAgilytix.


Essential Responsibilities

 

  • Lead the assay development, validation, and sample analysis of biologics, proteins, peptides, ADCs, and/or biomarkers, using various techniques including chromatographic and mass spectrometric assays (LC/MS) for support of preclinical, clinical and product release studies. Experience in mass spectrometry for bioanalysis is required.
  • Plan and direct experimental design for junior staff
  • Drive bioanalytical projects to align with client timelines
  • Frequent communication with clients to discuss technical details and provide project updates.
  • Author documents (methods, SOPs, reports)
  • Statistical analysis of bioanalytical data
  • Review of documentation

Minimum Acceptable Qualifications

 
Education/Experience:

 

  • Bachelor's degree in chemistry, biotechnology, biochemistry, or related field with between 6-12 years' experience in a scientific laboratory environment; or MS or PhD with equivalent experience
  • A thorough knowledge of regulatory guidance and industry best practices for LC/MS, and other large molecule assays
  • Demonstrated expertise in developing chromatographic and mass spectrometric assays including LC/MS and LC/MS/MS for bioanalytical studies by extracting analytes of interest from complex biological matrices using protein precipitation, liquid-liquid, solid phase, immunoprecipitation or other extraction technique
  • Advanced capabilities in data analysis, data visualization statistical analysis
  • Microsoft Word, Excel, Sciex OS/Analyst, MassLynx, XCalibur, Chromeleon, Watson LIMS, JMP, Graphpad Prism
  • GDP, GLP, GCLP, GCP

Skills:
 

  • Experience with development, validation and execution of chromatographic and mass spectrometric assays (LC/MS), and/or ability to perform most tasks associated with custom research planning and bench work
  • A knack for designing efficient and impactful experiments
  • Experience working in a regulated environment, with a thorough understating of GDP, GLP, GCLP, GCP
  • Independence, enthusiasm, openness, and adaptability
  • Demonstrated effective communication skills
  • The ability to inspire others to do their best work and drive results
  • Excellent customer service skills (internal and external)

Working Environment

  • Routinely laboratory/clinical environment and office work
  • Exposure to biological fluids with potential exposure to infectious organisms
  • Rare exposure to skin and lung irritants, radiation, toxic materials, and hazardous waste
  • Personal protective equipment required, such as protective eyewear, garments, and gloves
  • Exposure to fluctuating and/or extreme noise on rare occasions
  • Frequently interacts with others to obtain or relate information to diverse groups and clients
  • Works independently with little guidance or reliance on oral or written instructions and plans work schedules to meet goals

Physical Demands (examples):

  • Ability to access and use a variety of mass spectrometers and computer software for instrument control and data analysis
  • Ability to perform under stress and multi-task
  • May have to move a gas cylinder if facilities resource is not available
  • Regular and consistent attendance

    Position Type and Expected Hours of Work

    • This is a full-time position
    • Some flexibility in hours is allowed, but the employee must be available during the “core” work hours as published in the BioAgilytix Employee Handbook
    • Occasional weekend, holiday, and evening work required

    Weitere Details

    • Entgelttyp Gehalt
    Diese Ausschreibung ist inaktiv.
    Location on Google Maps
    • BioAgilytix Labs, 2300 Englert Drive, Durham, North Carolina, Vereinigte Staaten von Amerika